SCHEMBL769870

SCHEMBL769870

CCCCCCCCC=CCCCCCCCCNC(N)=O

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.62
FAAH O00519 3/20 0.61
MEN1 O00255 1/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C19 P33261 1/20 0.61
SOAT1 P35610 1/20 0.61
KMT2A Q03164 1/20 0.61
EPHX2 P34913 10/20 0.61
KDM4E B2RXH2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769868 1.00 SLC6A5 (0.62) SLC6A5FAAHMEN1TP53CYP1A2
SCHEMBL30349 1.00 SLC6A5 (0.62) SLC6A5FAAHMEN1TP53CYP1A2
SCHEMBL9800921 1.00 SLC6A5 (0.62) SLC6A5FAAHMEN1TP53CYP1A2
SCHEMBL31348788 1.00 SLC6A5 (0.62) SLC6A5FAAHMEN1TP53CYP1A2
SCHEMBL25711820 1.00 SLC6A5 (0.62) SLC6A5FAAHMEN1TP53CYP1A2
SCHEMBL3096362 1.00 SLC6A5 (0.62) SLC6A5FAAHMEN1TP53CYP1A2
SCHEMBL5146257 0.95 KDM4E (0.65) SOAT1KDM4E
SCHEMBL6332840 0.95 KDM4E (0.65) SOAT1KDM4E
SCHEMBL29619662 0.95 KDM4E (0.65) SOAT1KDM4E
SCHEMBL1702127 0.91 EPHX2 (0.60) SLC6A5EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297610-B1 N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase WARNER-LAMBERT COMPANY (US) 1991-03-13 EP claimed
EP-0297610-A1 N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase WARNER-LAMBERT COMPANY (US) 1989-01-04 EP claimed
US-12521350-B2 Liquid crystalline dosage form for administering a statin CUBOPHARM PTY LTD (AU) 2026-01-13 US disclosed
US-12521342-B2 Fast disintegrating tablet CUBOPHARM PTY LTD (AU) 2026-01-13 US disclosed
US-20240366510-A1 LIQUID CRYSTALLINE DOSAGE FORM FOR ADMINISTERING A STATIN ZEENAR ENTERPRISES PTY LTD (AU) 2024-11-07 US disclosed
US-20240350405-A1 FAST DISINTEGRATING TABLET ZEENAR ENTERPRISES PTY LTD (AU) 2024-10-24 US disclosed
WO-2023210218-A1 LUBRICATING OIL COMPOSITION ENEOS株式会社 2023-11-02 WO disclosed
US-20230277463-A1 LIQUID CRYSTALLINE DOSAGE FORM FOR ADMINISTERING A STATIN ZEENAR ENTERPRISES PTY LTD (AU) 2023-09-07 US disclosed
US-11638698-B2 Liquid crystalline dosage form for administering a statin ZEENAR ENTERPRISES PTY LTD (AU) 2023-05-02 US disclosed
CN-112912477-B Lubricating oil composition 引能仕株式会社 2022-11-11 CN disclosed
CN-112912478-B Lubricating oil composition 引能仕株式会社 2022-11-08 CN disclosed
EP-1534669-A4 UREA-, GLYCERATE- AND, HYDROXYAMIDE-HEADED HYDROCARBON CHAIN LYOTROPIC PHASES FORMING SURFACTANTS MAYNE PHARMA INT PTY LTD (AU) 2007-03-14 EP disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed
US-20050249665-A1 Urea-, glycerate- and, hydroxyamide-headed hydrocarbon chain lyotropic phases forming surfactants DBL AUSTRALIA PTY LTD. (AU) 2005-11-10 US disclosed
EP-1534669-A1 UREA-, GLYCERATE- AND, HYDROXYAMIDE-HEADED HYDROCARBON CHAIN LYOTROPIC PHASES FORMING SURFACTANTS DBL Australia PTY. LTD. (AU) 2005-06-01 EP disclosed
WO-2004022530-A1 UREA-, GLYCERATE- AND, HYDROXYAMIDE-HEADED HYDROCARBON CHAIN LYOTROPIC PHASES FORMING SURFACTANTS DBL AUSTRALIA PTY LTD (AU) 2004-03-18 WO disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
EP-0297610-B1 N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase WARNER-LAMBERT COMPANY (US) 1991-03-13 EP disclosed
EP-0297610-A1 N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase WARNER-LAMBERT COMPANY (US) 1989-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366510-A1 LIQUID CRYSTALLINE DOSAGE FORM FOR ADMINISTERING A STATIN HMGCR, LIPA, NPC1L1 SLC6A5 2257/4885FAAH 3027/4885MEN1 2115/4885
US-20230277463-A1 LIQUID CRYSTALLINE DOSAGE FORM FOR ADMINISTERING A STATIN HMGCR, LIPA, NPC1L1 SLC6A5 2257/4885FAAH 3027/4885MEN1 2115/4885
US-20050249665-A1 Urea-, glycerate- and, hydroxyamide-headed hydrocarbon chain lyotropic phases forming surfactants LIPA, HDHD5, UGCG SLC6A5 1081/4885FAAH 41/4885MEN1 3636/4885
US-11638698-B2 Liquid crystalline dosage form for administering a statin HMGCR, LIPA, NPC1L1 SLC6A5 2257/4885FAAH 3027/4885MEN1 2115/4885
US-20240350405-A1 FAST DISINTEGRATING TABLET SI, DSC1, STOM SLC6A5 2804/4885FAAH 2990/4885MEN1 2994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.