Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | FDPS | P14324 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857851 | 1.00 | MAPT (0.53) | MAPTCYP1A2CYP2C19CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL28129499 | 0.86 | CYP2C19 (0.49) | MAPTCYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL10716557 | 0.82 | MAPT (0.48) | MAPTCYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL19909042 | 0.80 | RAB9A (0.52) | MAPTCYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL11915503 | 0.80 | RAB9A (0.56) | MAPTCYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL2308076 | 0.78 | TSHR (0.39) | MAPTCYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL15368480 | 0.76 | NPC1 (0.61) | MAPTCYP1A2CYP2C19RAB9ANPC1 | |
| SCHEMBL15209522 | 0.76 | ALDH1A1 (0.47) | RAB9ANPC1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9209140 | 0.76 | CA12 (0.46) | MAPTCYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL8380332 | 0.76 | RAB9A (0.45) | MAPTRAB9ANPC1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894850-A | Pyridopyrimidine onium salt compound and application thereof | 帕潘纳(北京)科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| US-5025096-A | Preparation of indole and indole derivatives | MINE SAFETY APPLIANCES COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| US-5025096-A | Preparation of indole and indole derivatives | MINE SAFETY APPLIANCES COMPANY (US) | 1991-06-18 | — | — | US | disclosed |