Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422797 | 0.76 | ADRB2 (0.41) | MEN1KMT2ATDP1ADRB2LMNA | |
| SCHEMBL9801326 | 0.69 | KMT2A (0.46) | MEN1KMT2ATDP1DRD2DRD4 | |
| SCHEMBL7220062 | 0.68 | MEN1 (0.43) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL10624106 | 0.67 | ADRB2 (0.46) | MEN1KMT2ATDP1ADRB2LMNA | |
| SCHEMBL21915154 | 0.65 | FFAR2 (0.49) | MEN1KMT2ATDP1ADRB2NPSR1 | |
| SCHEMBL10253668 | 0.64 | KMT2A (0.58) | MEN1KMT2ATDP1NPSR1LMNA | |
| SCHEMBL7034676 | 0.64 | MEN1 (0.46) | MEN1KMT2ATDP1NPSR1SMN1; SMN2 | |
| SCHEMBL681137 | 0.63 | ADRB2 (0.42) | MEN1KMT2ATDP1ADRB2NPSR1 | |
| SCHEMBL27536656 | 0.63 | BRD4 (0.52) | MEN1KMT2AADRB2SMN1; SMN2HPGD | |
| SCHEMBL19231609 | 0.62 | ADRB2 (0.45) | MEN1KMT2ATDP1ADRB2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999440-A | Phenylethyloxirane Intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0291795-B1 | HYDROXYALKYL TRIAZOLYL DERIVATIVES | BAYER AG (DE) | 1990-12-05 | — | — | EP | disclosed |
| US-4894383-A | Fungicidal hydroxyalkyl-triazolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-16 | — | — | US | disclosed |
| EP-0291795-A2 | Hydroxyalkyl triazolyl derivatives | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |