Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801448 | 0.69 | MEN1 (0.38) | SLC6A2SLC6A4SLC6A3LMNAMAPT | |
| SCHEMBL9801376 | 0.68 | KCNH2 (0.44) | ABCB11LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL4441743 | 0.68 | SPHK1 (0.32) | — | |
| SCHEMBL7540577 | 0.68 | SPHK1 (0.32) | — | |
| SCHEMBL7534497 | 0.68 | SPHK1 (0.32) | — | |
| SCHEMBL7562574 | 0.68 | SPHK1 (0.32) | — | |
| SCHEMBL28176487 | 0.67 | KCNH2 (0.47) | SLC6A2SLC6A4SLC6A3ABCB11LMNA | |
| SCHEMBL11678773 | 0.66 | SPHK1 (0.35) | — | |
| SCHEMBL6686877 | 0.66 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ADRB2SMN1; SMN2 | |
| SCHEMBL9145085 | 0.66 | ADRB2 (0.39) | SLC6A2SLC6A4SLC6A3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999440-A | Phenylethyloxirane Intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0291795-B1 | HYDROXYALKYL TRIAZOLYL DERIVATIVES | BAYER AG (DE) | 1990-12-05 | — | — | EP | disclosed |
| US-4894383-A | Fungicidal hydroxyalkyl-triazolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-16 | — | — | US | disclosed |
| EP-0291795-A2 | Hydroxyalkyl triazolyl derivatives | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |