Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644314 | 0.84 | ADRB2 (0.34) | TDP1ADRB2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9145085 | 0.81 | ADRB2 (0.39) | MEN1KMT2ATDP1ADRB2SLC6A4 | |
| SCHEMBL10422227 | 0.78 | ADRB2 (0.37) | TDP1ADRB2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9801371 | 0.69 | SLC6A2 (0.36) | ADRB2SLC6A4SLC6A2SLC6A3BRD4 | |
| SCHEMBL9801451 | 0.68 | TAAR1 (0.34) | MEN1KMT2ATDP1SLC6A4SLC6A2 | |
| SCHEMBL9719713 | 0.64 | ADRB2 (0.38) | TDP1ADRB2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9801316 | 0.62 | MEN1 (0.45) | MEN1KMT2ANPSR1TDP1ADRB2 | |
| SCHEMBL1283913 | 0.62 | SLC6A2 (0.41) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10876682 | 0.59 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3TP53TSHR | |
| SCHEMBL19231609 | 0.59 | ADRB2 (0.45) | MEN1KMT2ANPSR1TDP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999440-A | Phenylethyloxirane Intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | claimed |
| US-4999440-A | Phenylethyloxirane Intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0291795-B1 | HYDROXYALKYL TRIAZOLYL DERIVATIVES | BAYER AG (DE) | 1990-12-05 | — | — | EP | disclosed |
| US-4894383-A | Fungicidal hydroxyalkyl-triazolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-16 | — | — | US | disclosed |