⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL18244314 | 0.98 | — | — | |
| SCHEMBL22446868 | 0.98 | — | — | |
| SCHEMBL9278566 | 0.92 | — | — | |
| SCHEMBL9286272 | 0.81 | PARP1 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL28025301 | 0.79 | PARP1 (0.33) | — | |
| SCHEMBL2058181 | 0.78 | — | — | |
| SCHEMBL10560484 | 0.78 | — | — | |
| SCHEMBL14128015 | 0.78 | — | — | |
| SCHEMBL19527609 | 0.78 | SIGMAR1 (0.33) | — | |
| SCHEMBL19199020 | 0.77 | ROCK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| CN-116574050-A | Method for producing structure-directing agents | 庄信万丰股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115380132-A | Membrane electrode assembly for COx reduction | 十二益公司 | 2022-11-22 | — | — | CN | disclosed |
| US-20180244618-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | JOHNSON MATTHEY PLC (GB) | 2018-08-30 | — | — | US | disclosed |
| EP-3286163-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | Johnson Matthey Public Limited Company (GB) | 2018-02-28 | — | — | EP | disclosed |
| US-20180016231-A9 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2018-01-18 | — | — | US | disclosed |
| CN-107531629-A | Method for preparing structure directing agent | 庄信万丰股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| EP-2427425-B1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20170044160-A1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. | 2017-02-16 | — | — | US | disclosed |
| WO-2016172128-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-10-27 | — | — | WO | disclosed |
| US-20160304457-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | JOHNSON MATTHEY PLC (GB) | 2016-10-20 | — | — | US | disclosed |
| US-9315451-B2 | Tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20120135968-A1 | Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. | 2012-05-31 | — | — | US | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| US-3988342-A | TRANQUILIZERS | MERCK & CO., INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3981877-A | APPETITE STIMULANTS | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3981876-A | ANTIHISTAMINES, APPETITE STIMULANTS | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3968115-A | OR 11)-BROMO-10,11-DIHYDRO-5H-DIBENZO(A,D)-CYCLOHEPTEN-5-YLIDENE PIPERIDINE COMPOUNDSANTIHISTAMINE, APPETITE STIMULANT | MERCK & CO., INC. (US) | 1976-07-06 | — | — | US | disclosed |