Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557732 | 0.74 | ADORA1 (0.56) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL9424995 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1MAPTGAACYP2D6 | |
| SCHEMBL9382067 | 0.69 | KDM4E (0.43) | KDM4EALDH1A1MAPTGAACYP2D6 | |
| SCHEMBL9383926 | 0.67 | KDM4E (0.41) | KDM4EALDH1A1MAPTGAACYP2D6 | |
| SCHEMBL5107992 | 0.67 | KDM4E (0.44) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL10831986 | 0.66 | KDM4E (0.43) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL9388846 | 0.65 | KDM4E (0.37) | KDM4E | |
| SCHEMBL7145868 | 0.65 | KDM4E (0.42) | KDM4EALDH1A1MAPTGAACYP2D6 | |
| SCHEMBL9425282 | 0.65 | KDM4E (0.39) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL9382528 | 0.63 | KDM4E (0.38) | KDM4EALDH1A1MAPTGAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008268-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-16 | — | — | US | disclosed |