Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 2/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382067 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1MAPTGAACHEK1 | |
| SCHEMBL10833000 | 0.71 | KDM4E (0.35) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL18091413 | 0.68 | KDM5B (0.40) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL19945607 | 0.68 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL5107992 | 0.67 | KDM4E (0.44) | KDM4EALDH1A1MAPTGAAPOLB | |
| SCHEMBL9383926 | 0.67 | KDM4E (0.41) | KDM4EALDH1A1MAPTGAAPOLB | |
| SCHEMBL512553 | 0.67 | NPSR1 (0.58) | KDM4EALDH1A1MAPTGAACHEK1 | |
| SCHEMBL9801808 | 0.66 | KDM4E (0.40) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL9425282 | 0.65 | KDM4E (0.39) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL9383309 | 0.65 | KDM4E (0.39) | KDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4577018-A | 2,3-Diamino-substituted-4(3H)-pyrimidinones and platinum chelates | AMERICAN CYANAMID COMPANY (US) | 1986-03-18 | — | — | US | claimed |
| US-4577018-A | 2,3-Diamino-substituted-4(3H)-pyrimidinones and platinum chelates | AMERICAN CYANAMID COMPANY (US) | 1986-03-18 | — | — | US | disclosed |