Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 7/20 | 0.32 |
| ▸ | DRD2 | P14416 | 7/20 | 0.32 |
| ▸ | HTR2A | P28223 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9592781 | 0.85 | HTR1A (0.31) | HTR1ADRD2HTR2A | |
| SCHEMBL9388846 | 0.75 | KDM4E (0.37) | KDM4E | |
| SCHEMBL3785984 | 0.72 | GAA (0.47) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL12943501 | 0.72 | DRD2 (0.53) | KDM4EHTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL5623016 | 0.72 | DRD2 (0.48) | HTR1ADRD2HTR2AALDH1A1MAPT | |
| SCHEMBL9386581 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPTGAA | |
| SCHEMBL3521123 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL13925636 | 0.70 | KDM4E (0.40) | KDM4EHTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL7318656 | 0.70 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL9382067 | 0.68 | KDM4E (0.43) | KDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284854-A | Antiserotonin. antihistamine agents; for sleep disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-02-08 | — | — | US | disclosed |
| US-5256659-A | Antiserotonine agents, antihistamines for nervous system disorders or psychological disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-10-26 | — | — | US | disclosed |
| US-5140029-A | Administering for nervous system, sleep or psychotic disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-08-18 | — | — | US | disclosed |
| US-5008268-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-16 | — | — | US | disclosed |