Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379440 | 0.86 | CFTR (0.45) | GRM2POLBFASNCFTR | |
| SCHEMBL1499434 | 0.86 | CFTR (0.45) | GRM2POLBFASNCFTR | |
| SCHEMBL4624725 | 0.86 | CFTR (0.45) | GRM2POLBFASNCFTR | |
| SCHEMBL27260115 | 0.86 | CFTR (0.45) | GRM2POLBFASNCFTR | |
| SCHEMBL9802435 | 0.80 | SPHK1 (0.48) | ALDH1A1 | |
| SCHEMBL9132881 | 0.77 | SLC5A2 (0.36) | ALDH1A1 | |
| SCHEMBL27917653 | 0.77 | HTR7 (0.36) | GRM2 | |
| SCHEMBL14450121 | 0.72 | TSHR (0.39) | HTTALDH1A1 | |
| SCHEMBL13964549 | 0.72 | SLC5A2 (0.49) | ALDH1A1 | |
| SCHEMBL8857978 | 0.72 | SLC5A2 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228045-B1 | AROMATIC THIOETHERS | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| US-4785004-A | ANTIALLERGENS, ANTIHISTAMINES | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0228045-A2 | Aromatic thioethers | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |