Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802263 | 0.94 | ELANE (0.64) | ELANELMNACES2CES1ALDH1A1 | |
| SCHEMBL21504942 | 0.89 | ELANE (0.52) | ELANELMNACES2CES1ALDH1A1 | |
| SCHEMBL9802818 | 0.85 | ELANE (0.52) | ELANELMNACES2CES1ALDH1A1 | |
| SCHEMBL9802822 | 0.85 | ELANE (0.52) | ELANELMNACES2CES1ALDH1A1 | |
| Benzoin SCHEMBL11787509 | 0.82 | LMNA (0.64) | ELANELMNACES2CES1ALDH1A1 | |
| SCHEMBL12412503 | 0.82 | ELANE (0.49) | ELANECES2CES1ALDH1A1KMT2A | |
| SCHEMBL10707039 | 0.80 | ELANE (0.55) | ELANELMNAALDH1A1HPGDKMT2A | |
| Benzoin SCHEMBL812299 | 0.80 | LMNA (0.75) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL11786930 | 0.80 | LMNA (0.75) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL29682204 | 0.79 | LMNA (0.59) | ELANELMNACES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985198-A | (METH)ACRYLOYLOXYBENZOIC ACID POLYMERS | G-C DENTAL INDUSTRIAL CORP. (JP) | 1991-01-15 | — | — | US | disclosed |