SCHEMBL12412503

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21504942	0.82	ELANE (0.52)	ELANEMAPTKMT2AATMALDH1A1
	SCHEMBL9802271	0.82	ELANE (0.64)	ELANEMAPTKMT2AATMALDH1A1
	SCHEMBL9802263	0.80	ELANE (0.64)	ELANEMAPTKMT2AATMALDH1A1
	Carbamic Acid SCHEMBL23407287	0.79	CA1 (0.50)	MAPTKMT2AALDH1A1CYP1A2MEN1
	SCHEMBL12412504	0.78	ABCG2 (0.44)	KMT2AALDH1A1CYP1A2MEN1NPC1
	Acetic Acid SCHEMBL3368380	0.77	CES2 (0.56)	MAPTKMT2AALDH1A1MEN1NPC1
	SCHEMBL139044	0.77	CES2 (0.59)	MAPTKMT2AALDH1A1MEN1NPC1
	SCHEMBL14181968	0.76	CES2 (0.48)	KMT2AALDH1A1MEN1GAARXRA
	SCHEMBL9802818	0.76	ELANE (0.52)	ELANEKMT2AALDH1A1CYP1A2MEN1
	SCHEMBL450454	0.76	ELANE (0.61)	ELANEMAPTKMT2AATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.