Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27628915 | 1.00 | IDO1 (0.54) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL1048398 | 0.82 | IDO1 (0.54) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL1048397 | 0.82 | IDO1 (0.54) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL10263844 | 0.82 | IDO1 (0.59) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL29624531 | 0.82 | IDO1 (0.54) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL28743537 | 0.82 | IDO1 (0.54) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL28743534 | 0.82 | IDO1 (0.54) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL8347342 | 0.81 | ACP3 (0.50) | IDO1TAAR1ACP3HTR2AHTR2B | |
| SCHEMBL5120041 | 0.80 | ALDH1A1 (0.51) | IDO1TAAR1ACP3MEN1KMT2A | |
| SCHEMBL5120039 | 0.80 | ALDH1A1 (0.51) | IDO1TAAR1ACP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848441-B | N-substituted benzoyl hydrazone compound and preparation method and application thereof | 山东中新科农生物科技有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-111848441-A | N-substituted benzoyl hydrazone compound and preparation method and application thereof | 朱翠萍 | 2020-10-30 | — | — | CN | claimed |
| CN-111848441-B | N-substituted benzoyl hydrazone compound and preparation method and application thereof | 山东中新科农生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-111848441-A | N-substituted benzoyl hydrazone compound and preparation method and application thereof | 朱翠萍 | 2020-10-30 | — | — | CN | disclosed |
| CN-106748695-B | Preparation method of m-trifluoromethyl cinnamaldehyde | 常州市阳光药业有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-105439818-A | Synthesis method of cinacalcet intermediate 3-(3-trifluoromethylphenyl) propanol | SUZHOU HUIHE PHARM CO LTD | 2016-03-30 | — | — | CN | disclosed |
| EP-0228045-B1 | AROMATIC THIOETHERS | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| US-4785004-A | ANTIALLERGENS, ANTIHISTAMINES | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |