SCHEMBL1048398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1048397	1.00	IDO1 (0.54)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL27628915	0.82	IDO1 (0.54)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL29624531	0.82	IDO1 (0.54)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL28743537	0.82	IDO1 (0.54)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL28743534	0.82	IDO1 (0.54)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL9802295	0.82	IDO1 (0.54)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL10263844	0.82	IDO1 (0.59)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL1330066	0.81	TAAR1 (0.55)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL5703037	0.79	IDO1 (0.59)	IDO1TAAR1ACP3HTR2AHTR2B
	SCHEMBL39835	0.79	TAAR1 (0.56)	IDO1TAAR1ACP3HTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.