Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577886 | 0.81 | — | — | |
| SCHEMBL10359173 | 0.80 | EPHX1 (0.40) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9803398 | 0.80 | LMNA (0.45) | LMNAALDH1A1NPSR1KDM4EMEN1 | |
| SCHEMBL9802840 | 0.77 | — | — | |
| SCHEMBL9802748 | 0.77 | — | — | |
| SCHEMBL9802837 | 0.77 | — | — | |
| SCHEMBL9802803 | 0.76 | OPRK1 (0.34) | — | |
| SCHEMBL10701502 | 0.73 | LMNA (0.38) | LMNAPOLBNPC1RAB9AMAPT | |
| SCHEMBL9803445 | 0.71 | KMT2A (0.47) | LMNAPOLBNPC1ALDH1A1GAA | |
| SCHEMBL11613244 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992518-A | Heat-resistant adhesives; matrix resins; dielectrics; composites; lamination | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4861885-A | Allylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid amides | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |