Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCND2 | P30279 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803346 | 0.92 | ALDH1A1 (0.42) | HPGDCSNK2A1PLK1PLK3BRD4 | |
| SCHEMBL7445206 | 0.83 | BRD4 (0.45) | HPGDCSNK2A1PLK1PLK3BRD4 | |
| SCHEMBL14856840 | 0.81 | CNR2 (0.49) | ALDH1A1CNR2CNR1MEN1KMT2A | |
| SCHEMBL9803168 | 0.81 | BRD4 (0.43) | HPGDCSNK2A1PLK1PLK3BRD4 | |
| SCHEMBL9802743 | 0.80 | HPGD (0.46) | HPGDCSNK2A1PLK1PLK3BRD4 | |
| SCHEMBL9802730 | 0.80 | BRD4 (0.47) | HPGDCSNK2A1PLK1PLK3BRD4 | |
| SCHEMBL7430749 | 0.78 | NPC1 (0.44) | HPGDCSNK2A1PLK1PLK3BRD4 | |
| SCHEMBL9802719 | 0.77 | HSD17B10 (0.43) | HPGDBRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL9803348 | 0.76 | BRD4 (0.41) | HPGDCSNK2A1PLK1PLK3BRD4 | |
| SCHEMBL7439352 | 0.75 | CSNK2A2 (0.56) | HPGDCSNK2A1BRD4LMNACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0338228-A2 | Use of quinoline-2,5-diones in a medicament having an analgesic, antipyretic and/or antiphlogistic activity | Dr. Karl Thomae GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |