Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448030 | 0.85 | BRD4 (0.63) | CSNK2A2CSNK2BCSNK2A1ABCG2BRD4 | |
| SCHEMBL7445206 | 0.79 | BRD4 (0.45) | CSNK2A1BRD4HPGDLMNA | |
| SCHEMBL9802743 | 0.79 | HPGD (0.46) | CSNK2A2CSNK2BCSNK2A1ABCG2BRD4 | |
| SCHEMBL9803168 | 0.77 | BRD4 (0.43) | CSNK2A2CSNK2BCSNK2A1ABCG2BRD4 | |
| SCHEMBL9803012 | 0.75 | HPGD (0.40) | CSNK2A2CSNK2BCSNK2A1ABCG2BRD4 | |
| SCHEMBL9802730 | 0.75 | BRD4 (0.47) | CSNK2A1BRD4HPGDMAOAMAOB | |
| SCHEMBL9802740 | 0.75 | HPGD (0.51) | BRD4HPGDMAOAMAOBLMNA | |
| SCHEMBL7430749 | 0.74 | NPC1 (0.44) | CSNK2A1BRD4HPGDLMNA | |
| SCHEMBL9803346 | 0.73 | ALDH1A1 (0.42) | CSNK2A2CSNK2BCSNK2A1ABCG2BRD4 | |
| SCHEMBL261530 | 0.72 | CSNK2B (1.00) | CSNK2A2CSNK2BCSNK2A1ABCG2ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472408-B1 | TWO 5- AMINO-5,6,7,8-TETRAHYDROQUINOLINE FRAGMENTS JOINED TOGETHER BY A DIVALENT LINKING GROUP; CHOLINESTERASE INHIBITORS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2002-10-29 | — | — | US | disclosed |
| US-20020156096-A1 | Dimeric compounds | HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) | 2002-10-24 | — | — | US | disclosed |
| EP-0489379-B1 | 5-amino-5,6,7,8-tetrahydroquinolines and related compounds, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5310914-A | Imination, reduction | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-05-10 | — | — | US | disclosed |
| US-5216164-A | Used for relieving memory dysfunction such as Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0489379-A1 | 5-amino-5,6,7,8-tetrahydroquinolines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-06-10 | — | — | EP | disclosed |
| US-5110815-A | Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156096-A1 | Dimeric compounds | ACHE, BCHE, CHRNA5 | CSNK2A2 1619/4885CSNK2B 1974/4885CSNK2A1 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.