Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.50 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184066 | 0.79 | NPC1 (0.54) | GAALMNAPOLBMEN1KMT2A | |
| SCHEMBL38660470 | 0.78 | MRGPRX4 (0.62) | GAAPTGS1ALDH1A1HTTRXFP1 | |
| SCHEMBL13676821 | 0.76 | KDM4E (0.48) | GAAALDH1A1HTTLMNAPOLB | |
| SCHEMBL21870341 | 0.76 | GAA (1.00) | GAAPTGS1ALDH1A1HTTRXFP1 | |
| SCHEMBL7344722 | 0.75 | MAPT (0.58) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL28633823 | 0.75 | PTGS1 (0.72) | GAAPTGS1NPSR1ALDH1A1HTT | |
| SCHEMBL11868617 | 0.75 | PTGS1 (0.72) | GAAPTGS1ALDH1A1HTTRXFP1 | |
| SCHEMBL30136206 | 0.75 | PTGS1 (0.72) | GAAPTGS1NPSR1ALDH1A1HTT | |
| SCHEMBL6431809 | 0.73 | PYGM (0.59) | GAAPTGS1ALDH1A1RXFP1LMNA | |
| SCHEMBL12154445 | 0.73 | NPSR1 (1.00) | GAANPSR1ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075325-A | Cardiovascular disorders | SYNTHELABO (FR) | 1991-12-24 | — | — | US | disclosed |
| US-5001159-A | Hypotensive, antiulcer, antiischemic agents; migraines, asthma epilepsy, anticoagulants; cardiovasculat disorders | SYNTHELABO (FR) | 1991-03-19 | — | — | US | disclosed |