Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672754 | 0.77 | KCNN4 (0.43) | KCNN4POLBALDH1A1RAB9ACA12 | |
| SCHEMBL4857148 | 0.77 | KCNN4 (0.43) | KCNN4POLBALDH1A1RAB9ACA12 | |
| SCHEMBL7641487 | 0.76 | KIF11 (0.44) | ALDH1A1MAPK1RAB9AKDM4ETDP1 | |
| SCHEMBL29421922 | 0.76 | LMNA (0.46) | KCNN4SMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL6746239 | 0.75 | MME (0.42) | KCNN4SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL6746235 | 0.75 | MME (0.42) | KCNN4SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL15898021 | 0.73 | MAPT (0.39) | KCNN4SMN1; SMN2POLBALDH1A1KIF11 | |
| Diethylamine SCHEMBL29401085 | 0.73 | KCNN4 (0.42) | KCNN4POLBALDH1A1KIF11CYP1A2 | |
| SCHEMBL2771122 | 0.73 | CYP1A2 (0.40) | KCNN4SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL9510102 | 0.73 | MME (0.41) | KCNN4SMN1; SMN2HPGDGAAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193904-B1 | AMINO ACID DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4743614-A | RESTORATIVE PROPERTIES INC IMMUNODEFICIENT HOSTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0193904-A2 | Amino acid derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |