Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803344 | 1.00 | HRH3 (0.39) | HRH3LMNAPOLBSLC6A3HTR7 | |
| SCHEMBL9803337 | 1.00 | HRH3 (0.39) | HRH3LMNAPOLBSLC6A3HTR7 | |
| SCHEMBL9803258 | 1.00 | HRH3 (0.39) | HRH3LMNAPOLBSLC6A3HTR7 | |
| SCHEMBL9803245 | 1.00 | HRH3 (0.39) | HRH3LMNAPOLBSLC6A3HTR7 | |
| SCHEMBL24817538 | 0.77 | SLC6A3 (0.42) | LMNAPOLBSLC6A3SLC18A2HTR2A | |
| SCHEMBL16055484 | 0.75 | NPC1 (0.41) | LMNASLC6A3HTR7SLC18A2HTR2A | |
| SCHEMBL3924677 | 0.75 | L3MBTL1 (0.43) | LMNASLC6A3SLC18A2HTR2A | |
| SCHEMBL3924679 | 0.75 | L3MBTL1 (0.43) | LMNASLC6A3SLC18A2HTR2A | |
| SCHEMBL12538444 | 0.75 | L3MBTL1 (0.43) | LMNASLC6A3SLC18A2HTR2A | |
| SCHEMBL17525816 | 0.73 | L3MBTL1 (0.43) | LMNAHTR7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049577-A | 2-pyrrolidone substituted dihydroxy alkanoic, alkenoic and alkynoic acids, compositions and HMG-CoA reductase inhibition therewith | E. R. SQUIBB & SONS, INC. (US) | 1991-09-17 | — | — | US | disclosed |