SCHEMBL9803363

SCHEMBL9803363

COc1ccc(-c2ccc(OC(=O)C(F)CC(C)C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.44
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
CTSS P25774 1/20 0.42
ALOX5 P09917 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
APP P05067 1/20 0.41
CYP2C19 P33261 1/20 0.41
ESR2 Q92731 1/20 0.41
ALDH1A1 P00352 5/20 0.40
HPGD P15428 4/20 0.40
KDM4E B2RXH2 4/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
GAA P10253 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9803754 0.85 ACACB (0.45) TAS1R3TAS1R1HPGDGAAMAPT
SCHEMBL9803484 0.83 RARB (0.48) TAS1R3TAS1R1CYP2C19NPC1SMN1; SMN2
SCHEMBL9803292 0.83 TAS1R3 (0.49) TAS1R3TAS1R1CYP2C19KMT2AMAPT
SCHEMBL9802947 0.82 ALOX5 (0.41) CTSKCTSLCTSBCTSSALOX5
SCHEMBL9803244 0.81 RARB (0.52) CYP2C19NPC1SMN1; SMN2TP53LMNA
SCHEMBL9803253 0.80 RARB (0.54) CYP2C19NPC1SMN1; SMN2TP53LMNA
SCHEMBL9803392 0.80 RARB (0.54) CYP2C19NPC1SMN1; SMN2TP53LMNA
SCHEMBL9803542 0.80 RARB (0.54) CYP2C19NPC1SMN1; SMN2TP53LMNA
SCHEMBL9803366 0.80 RARB (0.54) CYP2C19NPC1SMN1; SMN2TP53LMNA
SCHEMBL9802879 0.80 RARB (0.54) CYP2C19NPC1SMN1; SMN2TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0159872-B1 SMECTIC LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITIONS AJINOMOTO CO., INC. (JP) 1991-03-06 EP disclosed