Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340978 | 0.76 | CA1 (0.34) | MAPTHPGDALDH1A1 | |
| SCHEMBL9455488 | 0.69 | SRD5A1 (0.46) | MAPTHPGDKDM4EALDH1A1GAA | |
| SCHEMBL9797169 | 0.67 | KDM4E (0.34) | MAPTHPGDKDM4EALDH1A1GAA | |
| SCHEMBL10182573 | 0.65 | — | — | |
| SCHEMBL2021592 | 0.65 | — | — | |
| SCHEMBL4181392 | 0.65 | — | — | |
| Hydrogen Sulfide SCHEMBL9272622 | 0.63 | TSHR (0.44) | MAPTHPGDKDM4EALDH1A1GAA | |
| SCHEMBL13024393 | 0.62 | — | — | |
| SCHEMBL14382302 | 0.62 | — | — | |
| SCHEMBL9803041 | 0.62 | KDM4E (0.35) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068334-A | Analgesics and antipyretics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0338228-A2 | Use of quinoline-2,5-diones in a medicament having an analgesic, antipyretic and/or antiphlogistic activity | Dr. Karl Thomae GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |