Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979199 | 0.88 | HCAR3 (0.32) | HCAR3HCAR2 | |
| SCHEMBL4360772 | 0.76 | PTGDR2 (0.35) | HCAR3HCAR2 | |
| SCHEMBL980349 | 0.67 | CALCRL (0.33) | — | |
| SCHEMBL981352 | 0.67 | CALCRL (0.41) | HCAR3HCAR2 | |
| SCHEMBL1274652 | 0.65 | ELANE (0.33) | — | |
| SCHEMBL1274409 | 0.65 | ELANE (0.33) | — | |
| SCHEMBL1273412 | 0.61 | HCAR2 (0.38) | HCAR3HCAR2 | |
| SCHEMBL978963 | 0.56 | CALCRL (0.44) | HCAR3HCAR2 | |
| SCHEMBL976469 | 0.56 | CALCRL (0.37) | — | |
| SCHEMBL976466 | 0.56 | CALCRL (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021516-A1 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2271346-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021516-A1 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | CCKAR, CALCRL, CCKBR | HCAR3 97/4885HCAR2 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.