SCHEMBL9803540

SCHEMBL9803540

O=C(O)c1ccc2c(c1)C(=O)N(c1ccc(C(=O)c3cccc(N4C(=O)c5ccc(C(=O)O)cc5C4=O)c3)cc1)C2=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.72
HSD17B10 Q99714 1/20 0.65
S100B P04271 1/20 0.65
MEN1 O00255 6/20 0.63
KMT2A Q03164 6/20 0.63
ALDH1A1 P00352 3/20 0.63
MAPT P10636 2/20 0.63
RECQL P46063 1/20 0.63
RAB9A P51151 1/20 0.62
GFER P55789 1/20 0.62
NPSR1 Q6W5P4 2/20 0.61
CA1 P00915 4/20 0.60
CA9 Q16790 4/20 0.60
CA2 P00918 3/20 0.60
CA4 P22748 2/20 0.60
POLB P06746 2/20 0.58
MAPK1 P28482 1/20 0.58
HPSE Q9Y251 1/20 0.58
CA12 O43570 2/20 0.57
SCN2A Q99250 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9458520 0.96 TDP1 (0.77) TDP1HSD17B10S100BMEN1KMT2A
SCHEMBL4230581 0.92 S100B (0.74) TDP1HSD17B10S100BMEN1KMT2A
SCHEMBL9742475 0.90 CA9 (0.71) TDP1HSD17B10MEN1KMT2AALDH1A1
SCHEMBL10769332 0.88 S100B (0.63) TDP1HSD17B10S100BMEN1KMT2A
SCHEMBL9564308 0.87 HSD17B10 (0.72) TDP1HSD17B10S100BMEN1KMT2A
SCHEMBL9482780 0.85 APEX1 (0.66) TDP1HSD17B10MEN1KMT2AALDH1A1
SCHEMBL1618163 0.85 KMT2A (0.76) HSD17B10S100BMEN1KMT2AALDH1A1
SCHEMBL9339007 0.85 CA9 (0.77) TDP1HSD17B10MEN1KMT2AALDH1A1
SCHEMBL4234750 0.84 CA9 (0.77) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL12340942 0.83 TDP1 (0.60) TDP1HSD17B10S100BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0225537-B1 WHOLLY AROMATIC MESOGENIC POLYESTERIMIDES, THEIR FABRICATION AND USE BASF Aktiengesellschaft (DE) 1991-03-27 EP disclosed
US-RE33315-E Wholly aromatic mesomorphic polyester amide imides and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1990-08-28 US disclosed
EP-0349773-A2 Continuous preparation process of aromatic polycondensates BASF Aktiengesellschaft (DE) 1990-01-10 EP disclosed
EP-0231462-B1 WHOLLY AROMATIC MESOMORPHOUS POLYETHER ESTER IMIDES, THEIR PREPARATION AND USE BASF Aktiengesellschaft (DE) 1989-09-27 EP disclosed
US-4788272-A WEAR RESISTANCE BASF AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
US-4762906-A Wholly aromatic mesomorphic polyether ester imide and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
US-4728714-A Wholly aromatic mesomorphic polyester imides, the preparation and use thereof BASF AKTIENGESELLSCHAFT (DE) 1988-03-01 US disclosed
US-4728713-A Wholly aromatic mesomorphic polyester imides and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1988-03-01 US disclosed
US-4727129-A Wholly aromatic mesomorphic polyester amide imides and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
EP-0231462-A1 Wholly aromatic mesomorphous polyether ester imides, their preparation and use BASF Aktiengesellschaft (DE) 1987-08-12 EP disclosed
EP-0230547-A2 Wholly aromatic mesomorphous polyester amide imides, their preparation and their use BASF Aktiengesellschaft (DE) 1987-08-05 EP disclosed
EP-0227947-A2 Mesomorphous wholly aromatic polyester imides, their preparation and their use BASF Aktiengesellschaft (DE) 1987-07-08 EP disclosed
EP-0225529-A2 Wholly aromatic mesogenic polyesteramideimides, their fabrication and their use BASF Aktiengesellschaft (DE) 1987-06-16 EP disclosed
EP-0225537-A2 Wholly aromatic mesogenic polyesterimides, their fabrication and use BASF Aktiengesellschaft (DE) 1987-06-16 EP disclosed