Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803128 | 0.86 | GAA (0.57) | GAACYP2C19POLBL3MBTL1ATM | |
| SCHEMBL14084376 | 0.78 | KMT2A (0.51) | LTA4HPOLBALDH1A1KDM4ETERT | |
| SCHEMBL9803079 | 0.76 | CHRM2 (0.44) | POLBCACNA1BKDM4EKMT2A | |
| SCHEMBL14108063 | 0.76 | HDAC3 (0.68) | L3MBTL1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8156575 | 0.74 | CYP2C19 (0.57) | GAACYP2C19POLBL3MBTL1ATM | |
| SCHEMBL14803682 | 0.72 | KMT2A (0.57) | GAACYP2C19LTA4HPOLBL3MBTL1 | |
| SCHEMBL13676821 | 0.72 | KDM4E (0.48) | GAACYP2C19POLBL3MBTL1ATM | |
| SCHEMBL17354497 | 0.71 | CACNA1H (0.54) | POLBCACNA1HCACNA1BALDH1A1KDM4E | |
| SCHEMBL9803408 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4E | |
| SCHEMBL31494757 | 0.70 | L3MBTL1 (0.46) | GAACYP2C19POLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075325-A | Cardiovascular disorders | SYNTHELABO (FR) | 1991-12-24 | — | — | US | disclosed |
| US-5001159-A | Hypotensive, antiulcer, antiischemic agents; migraines, asthma epilepsy, anticoagulants; cardiovasculat disorders | SYNTHELABO (FR) | 1991-03-19 | — | — | US | disclosed |