Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803577 | 0.76 | GAA (0.53) | CACNA1BKDM4EPOLBKMT2A | |
| SCHEMBL9764367 | 0.73 | HTR2C (0.43) | KDM4EPOLBKMT2A | |
| SCHEMBL4933690 | 0.71 | DRD3 (0.49) | CACNA1BKDM4E | |
| SCHEMBL3870508 | 0.71 | TOP2A (0.43) | BRCA1SMN1; SMN2HIF1ATOP2ANPC1 | |
| SCHEMBL3872395 | 0.70 | HDAC3 (0.43) | CHRM2BRCA1SMN1; SMN2HIF1ATOP2A | |
| SCHEMBL9803408 | 0.69 | KDM4E (0.43) | HTR1BSMN1; SMN2HIF1AKDM4EHRH1 | |
| SCHEMBL21139494 | 0.69 | HTR2C (0.40) | SMN1; SMN2KDM4EPOLBKMT2A | |
| SCHEMBL1471135 | 0.69 | CHRM2 (0.58) | CHRM2NPC1POLBSLC2A1RAD52 | |
| SCHEMBL10116969 | 0.69 | KMT2A (0.55) | BRCA1SMN1; SMN2HIF1ATOP2AKDM4E | |
| SCHEMBL4334443 | 0.69 | ALDH1A1 (0.55) | SMN1; SMN2KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075325-A | Cardiovascular disorders | SYNTHELABO (FR) | 1991-12-24 | — | — | US | disclosed |
| US-5001159-A | Hypotensive, antiulcer, antiischemic agents; migraines, asthma epilepsy, anticoagulants; cardiovasculat disorders | SYNTHELABO (FR) | 1991-03-19 | — | — | US | disclosed |