Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27622496 | 0.93 | TDP1 (0.39) | LMNATDP1MEN1THRBBLM | |
| SCHEMBL97297 | 0.90 | LMNA (0.55) | LMNATDP1MEN1THRBBLM | |
| SCHEMBL29954357 | 0.90 | LMNA (0.55) | LMNATDP1MEN1THRBBLM | |
| Hydrochloric Acid SCHEMBL11758316 | 0.88 | LMNA (0.52) | LMNATDP1MEN1THRBBLM | |
| Acetic Acid SCHEMBL19133449 | 0.85 | TSHR (0.47) | LMNATDP1MEN1THRBBLM | |
| Thiourea SCHEMBL27964404 | 0.83 | LMNA (0.43) | LMNATDP1MEN1THRBBLM | |
| Thiosemicarbazide SCHEMBL27701286 | 0.78 | KMT2A (0.38) | LMNATDP1MEN1THRBBLM | |
| SCHEMBL20681341 | 0.77 | CYP2A6 (0.66) | LMNATDP1MEN1THRBBLM | |
| SCHEMBL1427931 | 0.74 | LMNA (0.46) | LMNATDP1MEN1THRBBLM | |
| SCHEMBL2844043 | 0.74 | ERN1 (0.55) | LMNATDP1MEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107703304-B | Oxybenzene derivative detection reagent, preparation method and tumor screening reagent | 深圳瑞达生物股份有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-113018457-B | Cyclodextrin inclusion compound and preparation method thereof | 北京远大九和药业有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-113018457-A | Cyclodextrin inclusion compound and preparation method thereof | 北京远大九和药业有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-1679872-A | Blackberrylily rhizome antiviral injection, preparation and venous medicine feeding blackberrylily rhizome antiviral injection thereof | NUOSHI PHARMACEUTICAL JILIN CO (CN) | 2005-10-12 | — | — | CN | disclosed |
| EP-0211392-B1 | LIQUID SHAMPOO COMPOSITION | Kao Corporation (JP) | 1991-03-27 | — | — | EP | disclosed |
| US-4678598-A | LOW TEMPERATURE STORAGE STABILITY | KAO CORPORATION (JP) | 1987-07-07 | — | — | US | disclosed |
| EP-0211392-A2 | Liquid shampoo composition | Kao Corporation (JP) | 1987-02-25 | — | — | EP | disclosed |