Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032320 | 0.86 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL11031570 | 0.82 | CYP1A2 (0.46) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL11032176 | 0.81 | CYP1A2 (0.48) | MEN1KMT2ATDP1MAPK1HRH3 | |
| SCHEMBL9804091 | 0.81 | NPSR1 (0.50) | MEN1KMT2ANPC1HRH3LMNA | |
| SCHEMBL9804140 | 0.80 | MAOA (0.45) | MEN1KMT2AHTT | |
| SCHEMBL9804070 | 0.80 | MEN1 (0.51) | MEN1KMT2AHRH3ALDH1A1SLC6A4 | |
| SCHEMBL9666814 | 0.79 | CYP1A2 (0.46) | MEN1KMT2AKDM4EHRH3HDAC1 | |
| SCHEMBL11034112 | 0.79 | CYP1A2 (0.46) | MEN1KMT2AKDM4EHRH3HDAC1 | |
| SCHEMBL9436179 | 0.79 | CYP1A2 (0.46) | MEN1KMT2AKDM4EHRH3HDAC1 | |
| SCHEMBL11031011 | 0.79 | CYP1A2 (0.46) | MEN1KMT2AKDM4EHRH3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | claimed |
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |
| EP-0335636-A1 | Antiviral compounds | SYNPHAR LABORATORIES INC. (CA) | 1989-10-04 | — | — | EP | disclosed |