SCHEMBL9804140

SCHEMBL9804140

Cc1cc(CCCCCCCOc2ccc3c(c2)[nH]c2ccccc23)on1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.45
KIF11 P52732 3/20 0.42
DYRK1A Q13627 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRE P78334 1/20 0.40
GABRA6 Q16445 1/20 0.40
GABRG1 Q8N1C3 1/20 0.40
GABRG3 Q99928 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625788 0.80 KIF11 (0.57) MAOAKIF11MEN1KMT2AGABRP
SCHEMBL9804036 0.80 MEN1 (0.47) MEN1KMT2AHTT
SCHEMBL11032320 0.79 MEN1 (0.51) MEN1KMT2A
SCHEMBL9804091 0.79 NPSR1 (0.50) MEN1KMT2A
SCHEMBL10513872 0.78 KIF11 (0.44) KIF11MEN1KMT2AGABRPGABRD
SCHEMBL13656510 0.77 GABRP (0.57) KIF11MEN1KMT2AGABRPGABRD
SCHEMBL9804050 0.75 KMT2A (0.42) MEN1KMT2AHTT
SCHEMBL16790723 0.75 GABRP (0.61) KIF11MEN1KMT2AGABRPGABRD
SCHEMBL11032176 0.74 CYP1A2 (0.48) MEN1KMT2A
SCHEMBL10327454 0.73 FAAH (0.43) MAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026848-A Antirhinovirus agents SYNPHAR LABORATORIES INCORPORATED (CA) 1991-06-25 US claimed
US-5026848-A Antirhinovirus agents SYNPHAR LABORATORIES INCORPORATED (CA) 1991-06-25 US disclosed
EP-0335636-A1 Antiviral compounds SYNPHAR LABORATORIES INC. (CA) 1989-10-04 EP disclosed