Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804062 | 0.84 | POLB (0.43) | SIRT2NR3C2HSD11B1KDM5AKDM5B | |
| SCHEMBL2357959 | 0.74 | MEN1 (0.46) | MEN1KMT2AFFAR4OXTRNR3C2 | |
| SCHEMBL30737481 | 0.74 | KMT2A (0.46) | MEN1KMT2AFFAR4OXTRNR3C2 | |
| SCHEMBL2399244 | 0.70 | MEN1 (0.43) | MEN1KMT2AFFAR4OXTRNR3C2 | |
| SCHEMBL5596095 | 0.67 | KCNH2 (0.53) | SIRT2KCNH2 | |
| SCHEMBL7614753 | 0.67 | KCNH2 (0.53) | SIRT2KCNH2 | |
| SCHEMBL7562217 | 0.67 | KCNH2 (0.53) | SIRT2KCNH2 | |
| SCHEMBL7217191 | 0.67 | KCNH2 (0.53) | SIRT2KCNH2 | |
| SCHEMBL7464785 | 0.67 | KCNH2 (0.53) | SIRT2KCNH2 | |
| SCHEMBL7562067 | 0.67 | KCNH2 (0.53) | SIRT2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |
| EP-0335636-A1 | Antiviral compounds | SYNPHAR LABORATORIES INC. (CA) | 1989-10-04 | — | — | EP | disclosed |