Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357959 | 0.81 | MEN1 (0.46) | KMT2AMEN1FFAR4NOTUMOXTR | |
| SCHEMBL14790220 | 0.81 | ALDH1A1 (0.37) | KMT2AMEN1FFAR4MAPTALDH1A1 | |
| SCHEMBL15790735 | 0.81 | ABHD16A (0.41) | KMT2AMEN1FFAR4NOTUMOXTR | |
| SCHEMBL30097884 | 0.81 | MAPK9 (0.42) | FFAR4MAPTALDH1A1ATMPOLB | |
| SCHEMBL1906019 | 0.81 | POLB (0.52) | MAPTALDH1A1POLBNPC1TSHR | |
| SCHEMBL2399244 | 0.81 | MEN1 (0.43) | KMT2AMEN1FFAR4NOTUMOXTR | |
| SCHEMBL30702580 | 0.75 | LMNA (0.43) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL19453172 | 0.75 | OXTR (0.48) | KMT2AMEN1NOTUMOXTRMAPT | |
| SCHEMBL9804041 | 0.74 | SIRT2 (0.41) | KMT2AMEN1FFAR4NOTUMOXTR | |
| SCHEMBL27858439 | 0.72 | POLB (0.57) | KMT2AMEN1NOTUMOXTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510505-A | Pyrimidopyrazoles derivatives and their use in medicine | 中国药科大学 | 2024-02-06 | — | — | CN | disclosed |