Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 3/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804041 | 0.84 | SIRT2 (0.41) | KDM5AKDM5BHSD11B1SIRT2ALDH1A1 | |
| SCHEMBL2987627 | 0.76 | POLB (0.48) | POLBGLSKDM5AKDM5BKDM4C | |
| SCHEMBL4859521 | 0.76 | POLB (0.48) | POLBKDM5AKDM5BKDM4CCNR1 | |
| SCHEMBL9803996 | 0.74 | DRD3 (0.46) | KDM4ENPC1LMNAMAPTHTT | |
| SCHEMBL9804066 | 0.73 | KCNA3 (0.51) | POLBKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL1195187 | 0.72 | NPC1 (0.50) | POLBGLSKDM5AKDM5BKDM4C | |
| SCHEMBL23116885 | 0.72 | POLB (0.52) | POLBCYP2C9MDM2HSP90AA1KDM4E | |
| SCHEMBL1906019 | 0.72 | POLB (0.52) | POLBCYP2C9MDM2MAPK14NPC1 | |
| SCHEMBL16815749 | 0.72 | POLB (0.52) | POLBKDM5AKDM5BKDM4CCYP2C9 | |
| SCHEMBL9804032 | 0.71 | RAB9A (0.45) | CYP2C9KDM4ENPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |
| EP-0335636-A1 | Antiviral compounds | SYNPHAR LABORATORIES INC. (CA) | 1989-10-04 | — | — | EP | disclosed |