SCHEMBL9804073

SCHEMBL9804073

Cc1cnsc1CCCCCCOc1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 8/20 0.52
SLC6A4 P31645 2/20 0.52
HRH1 P35367 1/20 0.50
KCNA3 P22001 1/20 0.49
MCL1 Q07820 2/20 0.45
HTR1D P28221 2/20 0.45
HRH3 Q9Y5N1 4/20 0.44
HTR2A P28223 2/20 0.44
HTR7 P34969 2/20 0.44
HTR6 P50406 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804044 0.81 NCF1 (0.41)
SCHEMBL9804001 0.79 NPC1 (0.45) HRH3
SCHEMBL16902854 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D
SCHEMBL16902849 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D
SCHEMBL11337403 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D
SCHEMBL16902853 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D
SCHEMBL16902840 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D
SCHEMBL16902855 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D
SCHEMBL16902852 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D
SCHEMBL16902863 0.76 KCNA3 (0.79) HTR1BSLC6A4HRH1KCNA3HTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026848-A Antirhinovirus agents SYNPHAR LABORATORIES INCORPORATED (CA) 1991-06-25 US claimed
US-5026848-A Antirhinovirus agents SYNPHAR LABORATORIES INCORPORATED (CA) 1991-06-25 US disclosed
EP-0335636-A1 Antiviral compounds SYNPHAR LABORATORIES INC. (CA) 1989-10-04 EP disclosed