Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15189278 | 0.98 | EPHX1 (0.46) | EPHX1ALDH1A1KDM4EEPHX2SIGMAR1 | |
| SCHEMBL11592017 | 0.74 | SIGMAR1 (0.54) | EPHX1EPHX2SIGMAR1MEN1KMT2A | |
| SCHEMBL9804119 | 0.73 | SMN1; SMN2 (0.52) | EPHX1ALDH1A1KDM4EEPHX2SIGMAR1 | |
| SCHEMBL3068845 | 0.73 | SIGMAR1 (0.44) | EPHX1ALDH1A1KDM4EEPHX2SIGMAR1 | |
| SCHEMBL8297620 | 0.72 | — | — | |
| SCHEMBL23862923 | 0.71 | — | — | |
| SCHEMBL827936 | 0.71 | SMN1; SMN2 (0.61) | EPHX1ALDH1A1KDM4EEPHX2KMT2A | |
| SCHEMBL15452504 | 0.71 | EPHX1 (0.42) | EPHX1ALDH1A1KDM4EEPHX2SIGMAR1 | |
| SCHEMBL22179283 | 0.71 | SIGMAR1 (0.38) | EPHX1ALDH1A1KDM4EEPHX2SIGMAR1 | |
| SCHEMBL3060799 | 0.71 | EPHX1 (0.57) | EPHX1ALDH1A1KDM4EEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003314-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-01-07 | — | — | WO | disclosed |