Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804159 | 0.95 | CYP2D6 (0.50) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL9804215 | 0.86 | KMT2A (0.47) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL14975485 | 0.86 | KMT2A (0.47) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL9804167 | 0.81 | HTR3E (0.41) | CYP2D6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9804122 | 0.81 | HTR3E (0.41) | CYP2D6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10336592 | 0.79 | HTR3E (0.52) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL9804178 | 0.78 | KMT2A (0.40) | CYP2D6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10797492 | 0.78 | CYP2D6 (0.54) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL10336590 | 0.78 | CYP2D6 (0.54) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL664328 | 0.77 | CYP2C19 (0.45) | CYP2D6HIF1AHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153616-B1 | HEAT-SENSITIVE RECORDING MATERIALS | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4652512-A | DIAZONIUM COMPOUND | KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0153616-A2 | Heat-sensitive recording materials | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-09-04 | — | — | EP | disclosed |