Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664329 | 1.00 | CYP2C19 (0.45) | CYP2C19CNR2TSPONPC1RAB9A | |
| SCHEMBL9804129 | 0.77 | CYP2D6 (0.45) | CYP2C19NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL22072470 | 0.73 | CNR2 (0.47) | CYP2C19CNR2TSPONPC1RAB9A | |
| SCHEMBL12031549 | 0.73 | NPC1 (0.67) | CNR2TSPONPC1RAB9AALDH1A1 | |
| SCHEMBL20218944 | 0.73 | LTB4R2 (0.62) | CNR2NPC1RAB9AGAATSHR | |
| SCHEMBL9804159 | 0.72 | CYP2D6 (0.50) | CYP2C19NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4237595 | 0.72 | CNR2 (0.58) | CYP2C19CNR2TSPONPC1RAB9A | |
| SCHEMBL3060610 | 0.71 | CYP2D6 (0.53) | NPC1RAB9AALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL16382907 | 0.69 | CYP2D6 (0.46) | CNR2NPC1RAB9ASMN1; SMN2CYP2D6 | |
| SCHEMBL14176611 | 0.69 | TSPO (0.73) | CYP2C19CNR2TSPONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846851-B2 | Methods of ring opening polymerization and catalysts therefor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-30 | — | — | US | claimed |
| US-20130158226-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-20 | — | — | US | claimed |
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-02-23 | — | — | US | claimed |
| US-8846851-B2 | Methods of ring opening polymerization and catalysts therefor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-30 | — | — | US | disclosed |
| US-8541477-B2 | Methods of depolymerizing terephthalate polyesters | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-8507640-B2 | Methods of ring opening polymerization and catalysts therefor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-08-13 | — | — | US | disclosed |
| US-20130158226-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2012121985-A2 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-09-13 | — | — | WO | disclosed |
| US-20120223270-A1 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY (SA) | 2012-09-06 | — | — | US | disclosed |
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120223270-A1 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | DDT, TRHDE, TERT | CYP2C19 2313/4885CNR2 4618/4885TSPO 1859/4885 |
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | OGFOD1, PCNA, ODC1 | CYP2C19 3758/4885CNR2 3807/4885TSPO 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.