Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 10/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 5/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804696 | 0.86 | MAPK14 (0.47) | MAPK14CETPFDFT1LTA4HEPHX2 | |
| SCHEMBL9804291 | 0.86 | MAPK14 (0.49) | MAPK14CETPFDFT1LTA4HEPHX2 | |
| SCHEMBL9557901 | 0.86 | MAPK14 (0.48) | MAPK14CETPFDFT1LTA4HEPHX2 | |
| SCHEMBL10446484 | 0.82 | LTA4H (0.52) | MAPK14CETPFDFT1LTA4HEPHX2 | |
| SCHEMBL9682172 | 0.82 | MAPK14 (0.45) | MAPK14CETPFDFT1LTA4HEPHX2 | |
| SCHEMBL10649121 | 0.81 | MAPK14 (0.44) | MAPK14CETPFDFT1LTA4HEPHX2 | |
| SCHEMBL9560923 | 0.81 | MAPK14 (0.48) | MAPK14CETPLTA4HEPHX2NR3C1 | |
| SCHEMBL10545123 | 0.80 | FDFT1 (0.43) | MAPK14CETPFDFT1 | |
| SCHEMBL9558339 | 0.79 | FDFT1 (0.43) | MAPK14CETPFDFT1CHRM2CHRM1 | |
| SCHEMBL10544259 | 0.79 | FDFT1 (0.41) | MAPK14CETPFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | claimed |
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |