Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | CETP | P11597 | 9/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560662 | 0.89 | CETP (0.43) | MAPK14CETPTACR1MRGPRX4FFAR1 | |
| SCHEMBL8675859 | 0.87 | MAPK14 (0.49) | MAPK14CETPTACR1MRGPRX4NR3C1 | |
| SCHEMBL9560464 | 0.86 | MAPK14 (0.47) | MAPK14CETPTACR1MRGPRX4NR3C1 | |
| SCHEMBL9560889 | 0.86 | MAPK14 (0.49) | MAPK14CETPTACR1MRGPRX4NR3C1 | |
| SCHEMBL9560443 | 0.86 | LTA4H (0.48) | CETPMRGPRX4FFAR1LTA4HFFAR4 | |
| SCHEMBL9785863 | 0.82 | MAPK14 (0.45) | MAPK14CETPTACR1MRGPRX4 | |
| SCHEMBL9804241 | 0.81 | MAPK14 (0.48) | MAPK14CETPNR3C1LTA4HEPHX2 | |
| SCHEMBL10854916 | 0.81 | NPC1 (0.43) | MAPK14CETPTACR1FFAR1FFAR4 | |
| SCHEMBL10856880 | 0.80 | NPC1 (0.41) | MAPK14CETPTACR1FFAR1FFAR4 | |
| SCHEMBL9560424 | 0.80 | MAPK14 (0.40) | MAPK14CETPTACR1MRGPRX4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |