Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804247 | 1.00 | CETP (0.42) | CETPFFAR1FFAR4MAPK14CHRM2 | |
| SCHEMBL9804404 | 0.89 | CETP (0.40) | CETPFFAR1FFAR4MAPK14CHRM2 | |
| SCHEMBL9804397 | 0.89 | CETP (0.40) | CETPFFAR1FFAR4MAPK14CHRM2 | |
| SCHEMBL9804338 | 0.87 | LTA4H (0.46) | CETPFFAR1FFAR4MAPK14CHRM2 | |
| SCHEMBL9804345 | 0.87 | LTA4H (0.46) | CETPFFAR1FFAR4MAPK14CHRM2 | |
| SCHEMBL9804448 | 0.87 | LTA4H (0.46) | CETPFFAR1FFAR4MAPK14CHRM2 | |
| SCHEMBL7932267 | 0.84 | AKR1C3 (0.42) | CETPFFAR1FFAR4MAPK14KDM4E | |
| SCHEMBL7932271 | 0.84 | AKR1C3 (0.42) | CETPFFAR1FFAR4MAPK14KDM4E | |
| SCHEMBL9561674 | 0.83 | CETP (0.42) | CETPFFAR1FFAR4MAPK14TSHR | |
| SCHEMBL9561670 | 0.83 | CETP (0.42) | CETPFFAR1FFAR4MAPK14TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |