Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.55 |
| ▸ | RORC | P51449 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP3A5 | P20815 | 6/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913686 | 0.81 | CYP19A1 (0.72) | CYP19A1RORCCYP3A4CYP3A5 | |
| SCHEMBL9804331 | 0.80 | CYP3A4 (0.51) | CYP19A1RORCCYP3A4CYP3A5 | |
| SCHEMBL10692529 | 0.77 | CYP19A1 (0.58) | CYP19A1RORCCYP3A4CYP3A5CYP11B1 | |
| SCHEMBL4558274 | 0.75 | CYP19A1 (0.65) | CYP19A1RORCCYP3A4CYP3A5 | |
| SCHEMBL10957179 | 0.74 | PTPN1 (0.48) | CYP19A1RORCCYP3A4 | |
| SCHEMBL16474154 | 0.73 | RORC (0.92) | RORC | |
| SCHEMBL7685830 | 0.72 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL26632885 | 0.71 | CYP1A2 (0.56) | CYP3A4 | |
| SCHEMBL30536498 | 0.71 | CYP1A2 (0.56) | CYP3A4 | |
| SCHEMBL4473850 | 0.71 | CYP19A1 (0.64) | CYP19A1RORCCYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194579-B1 | 3-PYRIDYLMETHYLNAPHTHYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | disclosed |