SCHEMBL9804453

SCHEMBL9804453

CN(C1=CCCCC1)[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40
CXCR3 P49682 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776734 0.77 ALDH1A1 (0.41) ALDH1A1RAB9ACXCR3
SCHEMBL517221 0.77
SCHEMBL3966810 0.75 ALDH1A1 (0.40) ALDH1A1RAB9ACXCR3
SCHEMBL15457506 0.75 ALDH1A1 (0.40) ALDH1A1RAB9ACXCR3
SCHEMBL31671011 0.71 ALDH1A1 (0.41) ALDH1A1RAB9ACXCR3
SCHEMBL516345 0.71 ALDH1A1 (0.39) ALDH1A1RAB9A
SCHEMBL10870183 0.70 ALDH1A1 (0.44) ALDH1A1RAB9ACXCR3
SCHEMBL15457509 0.70 ALDH1A1 (0.37) ALDH1A1RAB9ACXCR3
SCHEMBL5697315 0.69 ALDH1A1 (0.38) ALDH1A1RAB9ACXCR3
SCHEMBL517183 0.69 ALDH1A1 (0.34) ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413464-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-20 EP disclosed
EP-0413465-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-20 EP disclosed
EP-0405786-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-02 EP disclosed
US-4981827-A Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-01 US disclosed
EP-0323082-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-07-05 EP disclosed