Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804906 | 0.87 | CCR1 (0.34) | CCR1CYP19A1 | |
| SCHEMBL9804652 | 0.80 | CTDSP1 (0.32) | CTDSP1 | |
| SCHEMBL9804810 | 0.79 | CYP19A1 (0.39) | CCR1EBPSIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL10371879 | 0.79 | CYP19A1 (0.36) | CCR1EBPSIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL10372451 | 0.76 | TDP1 (0.45) | CCR1EBPSIGMAR1L3MBTL1CYP19A1 | |
| SCHEMBL9021740 | 0.76 | CCR1 (0.40) | CCR1EBPSIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL9804907 | 0.75 | CYP19A1 (0.43) | CCR1EBPSIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL9804637 | 0.75 | CTDSP1 (0.35) | CCR1EBPSIGMAR1CTDSP1 | |
| SCHEMBL10466714 | 0.74 | CCR1 (0.40) | CCR1EBPSIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL8036943 | 0.73 | CCR1 (0.34) | CCR1EBPSIGMAR1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276920-B1 | (2-CYANO-2-(PHENYL OR NAPHTHYL)-2-SUBSTITUTED-ETHYL) PYRAZINES, PYRIMIDINES AND PYRIDAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |