Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.88 |
| ▸ | TK2 | O00142 | 2/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.60 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.60 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.56 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.55 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.55 |
| ▸ | TYMP | P19971 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL3515238 | 1.00 | PYGM (0.88) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL2579064 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL654693 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL309063 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL158910 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL15810788 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL6758925 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL12143148 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL41201 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 | |
| SCHEMBL19657168 | 0.95 | PYGM (0.97) | PYGMTK2P2RY2P2RY6P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62265299-A | — | — | None | — | — | JP | disclosed |
| EP-0226753-B1 | ALPHA-TOCOPHEROL (HALO) URIDINE PHOSPHORIC ACID DIESTER, SALTS THEREOF, AND METHODS FOR PRODUCING THE SAME | Senju Pharmaceutical Co., Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4742163-A | ANTITUMOR, ANTIINFLAMMATORY | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| JP-S62265299-A | PRODUCTION OF ALPHA-TOCOPHEROL, URIDINEPHOSPHORIC ACID DIESTER AND HALOGEN-SUBSTITUTED COMPOUND THEREOF OR THEIR SALT | SENJIYU SEIYAKU KK | 1987-11-18 | — | — | JP | disclosed |
| EP-0226753-A2 | Alpha-tocopherol (halo) uridine phosphoric acid diester, salts thereof, and methods for producing the same | Senju Pharmaceutical Co., Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |