SCHEMBL9804844

SCHEMBL9804844

CC1CCC2=C(C1)C(=O)N(c1cc(O)c(Cl)cc1F)C2=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.37
GRM7 Q14831 1/20 0.36
GRM4 Q14833 1/20 0.36
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8687000 0.86 PPOX (0.39) PPOXGRM7GRM4
SCHEMBL9805046 0.83 PPOX (0.57) PPOXSMN1; SMN2
SCHEMBL9804877 0.82 PPOX (0.38) PPOX
SCHEMBL5318631 0.82 GRM7 (0.46) PPOXGRM7GRM4
SCHEMBL30566778 0.82 GRM7 (0.46) PPOXGRM7GRM4
SCHEMBL9804968 0.81 PPOX (0.53) PPOX
SCHEMBL9804880 0.81 PPOX (0.53) PPOX
SCHEMBL8759918 0.80 PPOX (0.48) PPOX
SCHEMBL9814978 0.79 PPOX (0.38) PPOXGRM7GRM4
SCHEMBL9805127 0.78 PPOX (0.41) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990176-A Selective, tolerated by cultivated plants CIBA-GEIGY CORPORATION (US) 1991-02-05 US disclosed
EP-0259264-A1 4-Methyl phthalimides CIBA-GEIGY AG (CH) 1988-03-09 EP disclosed