SCHEMBL9804877

SCHEMBL9804877

COC(=O)Cc1cc(N2C(=O)C3=C(CC(C)CC3)C2=O)c(F)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPOX P50336 2/20 0.38
RORC P51449 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10699614 0.84 PPOX (0.52) PPOX
SCHEMBL9804844 0.82 PPOX (0.37) PPOX
SCHEMBL9805046 0.80 PPOX (0.57) PPOX
SCHEMBL9804880 0.79 PPOX (0.53) PPOX
SCHEMBL10843729 0.76 PPOX (0.42) PPOX
SCHEMBL9804968 0.75 PPOX (0.53) PPOX
SCHEMBL9805127 0.75 PPOX (0.41) PPOX
SCHEMBL9804778 0.75 PPOX (0.48) PPOX
SCHEMBL8759744 0.75 PPOX (0.41) PPOX
SCHEMBL10714203 0.74 GRM7 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259264-A1 4-Methyl phthalimides CIBA-GEIGY AG (CH) 1988-03-09 EP claimed
US-4990176-A Selective, tolerated by cultivated plants CIBA-GEIGY CORPORATION (US) 1991-02-05 US disclosed
EP-0259264-A1 4-Methyl phthalimides CIBA-GEIGY AG (CH) 1988-03-09 EP disclosed