Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121989 | 0.93 | CYP2C9 (0.49) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL9032779 | 0.90 | CYP2C9 (0.57) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL10366225 | 0.88 | TSHR (0.51) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL9032248 | 0.84 | CYP2C9 (0.51) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL4790038 | 0.82 | CYP2C9 (0.58) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL9234815 | 0.82 | CYP2C9 (0.51) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL28802628 | 0.80 | ABCB11 (0.63) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL9034239 | 0.79 | CYP2C9 (0.58) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL8199258 | 0.79 | TSHR (0.73) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL4881545 | 0.79 | LMNA (0.61) | CYP2C9TSHRKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994461-A | Vasodilators; treating cardiovascular disorders | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0394243-A1 | PROCESS FOR MANUFACTURING CARBOXYLIC ACIDS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1990-10-31 | — | — | EP | disclosed |
| EP-0343193-A1 | 1,4-DIHYDROPYRIDINE ENANTIOMERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-11-29 | — | — | EP | disclosed |
| EP-0296316-A1 | 1,4-Dihydropyridine enantiomers | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1988-12-28 | — | — | EP | disclosed |
| WO-1988009331-A1 | PROCESS FOR MANUFACTURING CARBOXYLIC ACIDS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1988-12-01 | — | — | WO | disclosed |
| EP-0287828-A1 | Intermediates and their preparation | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988007525-A1 | 1,4-DIHYDROPYRIDINE ENANTIOMERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1988-10-06 | — | — | WO | disclosed |