Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14608877 | 0.79 | MAOB (0.46) | KMT2AALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL11262327 | 0.73 | KMT2A (0.60) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL21138207 | 0.73 | TDP1 (0.53) | TDP1SLC6A2SLC6A3KMT2ATSHR | |
| SCHEMBL20154268 | 0.70 | TDP1 (0.58) | TDP1SLC6A2SLC6A3KMT2ATSHR | |
| SCHEMBL20086322 | 0.70 | ALDH1A1 (0.49) | TDP1SLC6A2SLC6A3KMT2ATSHR | |
| SCHEMBL17965761 | 0.69 | TDP1 (0.61) | TDP1SLC6A2SLC6A3KMT2ATSHR | |
| SCHEMBL19775347 | 0.69 | TDP1 (0.56) | TDP1SLC6A2SLC6A3KMT2ATSHR | |
| SCHEMBL20074245 | 0.69 | TSHR (0.67) | TDP1SLC6A2SLC6A3KMT2ATSHR | |
| SCHEMBL8833118 | 0.69 | TDP1 (0.56) | TDP1SLC6A2SLC6A3KMT2ATSHR | |
| SCHEMBL17969774 | 0.69 | ALDH1A1 (0.56) | TDP1SLC6A2SLC6A3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3099058-A | — | — | None | — | — | JP | disclosed |
| JP-H0399058-A | FIVE-MEMBERED HETEROCYCLIC COMPOUND | KAKEN PHARMACEUT CO LTD | 1991-04-24 | — | — | JP | disclosed |