Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805088 | 0.94 | HTT (0.73) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL11169340 | 0.82 | HTT (0.68) | HTTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL8061323 | 0.81 | HTT (0.54) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL31619940 | 0.81 | PRKCZ (0.56) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL11184909 | 0.80 | HTT (0.64) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL9805097 | 0.80 | HTT (1.00) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL4461121 | 0.78 | HTT (0.51) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL27699148 | 0.78 | ALDH1A1 (0.58) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL10748815 | 0.77 | MAPT (0.55) | HTTSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL154900 | 0.76 | HTT (0.49) | HTTSMN1; SMN2ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419792-A1 | Pyrroles as costabilizers for vinylchloride polymerisate based mouldings | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | disclosed |
| EP-0419794-A1 | Costabilizers for vinyl chloride polymerisate based mouldings | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | disclosed |