Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805215 | 1.00 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL9805620 | 0.89 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL9805252 | 0.88 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL9805198 | 0.88 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL9805185 | 0.84 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL9805158 | 0.84 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL9805278 | 0.82 | ALDH1A1 (0.41) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL4864949 | 0.82 | ADK (0.67) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL9805093 | 0.79 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL9805553 | 0.78 | ADK (0.65) | PI4KAPI4K2BPI4K2API4KBADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041542-A | Antitumor-anticarcinogenic agents | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1991-08-20 | — | — | US | disclosed |