Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12834934 | 0.84 | GAA (0.54) | CA1CA2CA12CA9CA3 | |
| SCHEMBL179723 | 0.82 | ALDH1A1 (0.57) | CA1CA2CA12CA9CA3 | |
| Guanidine SCHEMBL811270 | 0.80 | CYP2D6 (0.61) | CA1CA2CA12CA9CA3 | |
| SCHEMBL9878066 | 0.78 | CYP2D6 (0.55) | CA1CA2CA12CA9CA3 | |
| SCHEMBL9029471 | 0.78 | HPN (0.50) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL1334815 | 0.77 | GAA (0.52) | CA1CA2CA12CA9CA3 | |
| SCHEMBL19632642 | 0.77 | GAA (0.46) | CA1CA2CA12CA9CA3 | |
| Thiourea SCHEMBL1577311 | 0.77 | CYP2D6 (0.58) | CA1CA2CA12CA9CA3 | |
| SCHEMBL27294672 | 0.76 | SMN1; SMN2 (0.50) | CA1CA2CA12CA9CA3 | |
| SCHEMBL27914208 | 0.76 | GAA (0.56) | CA1CA2CA12CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203509-B1 | Method for the quantitative determination of protein-C and an activating preparation for its implementation. | Pentapharm A.G. (CH) | 1991-04-03 | — | — | EP | claimed |
| US-4849403-A | CONVERSION OF ZYMOGEN INTO PROTEINASE; SNAKE VENOM | PENTAPHARM AG (CH) | 1989-07-18 | — | — | US | claimed |
| US-4849403-A | CONVERSION OF ZYMOGEN INTO PROTEINASE; SNAKE VENOM | PENTAPHARM AG (CH) | 1989-07-18 | — | — | US | disclosed |